Washington: Researchers found good anti-diabetic substance in the amorfrutin class of natural substances. It provides the raw material for liquorice candy and makes the stomach work smoothly.
Chosen as the “Medicinal plant 2012”, the root has been treasured in traditional healing since ancient times.
Researchers at the Max Planck Institute for Molecular Genetics in Berlin have now discovered that liquorice root also contains substances with an anti-diabetic effect.
These amorfrutins not only reduce blood sugar, they are also anti-inflammatory and are very well tolerated. Thus, they may be suitable for use in the treatment of complex metabolic disorders.
Natural substances have a surprising and often largely unexploited potential in the prevention and treatment of common diseases.
A team of researchers working with Sascha Sauer from the Max Planck Institute for Molecular Genetics in Berlin has now discovered that the plant from the papilionaceae or leguminous family might also be effective in the treatment of adult (type 2) diabetes.
“The health-beneficial effects are based on the fact that the amorfrutin molecules dock directly onto a receptor in the nucleus called PPAR (gamma),” explained Sascha Sauer.
“Although there are already drugs on the market that affect the PPAR (gamma) receptor, they are not selective enough in their effect and cause side effects like weight gain and cardio-vascular problems,” said Sascha Sauer.
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