Washington: A new study has found that eating a high-fat diet even for a short period may change the brain in ways that makes it harder to lose weight.
Researchers from the University of Washington School of Medicine looked at the brains f rodents that were bred to become obese and found that when placed on a high-fat diet.
The animals developed injuries to the hypothalamus, an area of the brain that controls the urge to eat and sends signals to stop eating when one is full.
“Within 24 hours of switching rodents to a high-fat diet, we found injury in the hypothalamus area,” Michael Schwartz, co-author of the study, said.
The researchers compared rats and mice that ate a high-fat diet with those that ate a regular diet over a four-week period. Within the first week, they found gliosis, an overgrowth of cells that is a sign that the brain has tried to heal itself from injury.
Stephen Hammes, chief endocrinologist at the University of Rochester Medical Center, who was not involved with the work, cautioned that the study was mostly done in rodents.
“We don’t know if humans respond the same way as rodents, but this study is still intriguing,” Hammes said.
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